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Best Early NFL Underdogs for Week Four: Back the Arizona Cardinals!

Best Early NFL Underdogs for Week Four: Back the Arizona Cardinals!

May 1, 2025 1:20 AM

Week four of the NFL season will be here before we know it. We’ve compiled a list of three early underdog bets you should consider making before the public bets them to death. 

Baltimore Ravens +3.5 (-110) with BovadaChicago Bears +3.5 (-107) with BovadaArizona Cardinals +2.0 (107) with Bovada

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Buffalo Bills vs Baltimore Ravens Odds, Line and Spread 

Money Line: Buffalo Bills ML -181 vs Baltimore Ravens ML +160 with Bovada

Spread: Buffalo Bills -3.5 (-107) vs Baltimore Ravens +3.0 (-110) with Bovada

A pair of 2-1 AFC teams meet in this clash between two sides with one thing in common; they both lost to Miami.

Buffalo is banged up, but they nearly defeated the Dolphins in Miami. They have five defensive starters out with an injury-riddled offensive line and still are 3.5 point away favorites here

Baltimore bounced back from a bad 4th quarter against Miami with a solid home victory over New England. The Ravens defense has been a bit shaky, but they’ve outscored their opponents by 22 points and without their 4th quarter collapse would be 3-0.

Important trends for this matchup;

Bills are 1-4 ATS in their last 5 meetings in BaltimoreHome team is 4-1 ATS in their last 5 meetings

Depending on the Bills injury status, the Ravens +160 ML is absolutely in play here as well, but the +3.5 points is probably the way to go for an early wager.  

Back Baltimore +3.5 points @ -110 With Bovada

Chicago Bears vs New York Giants Odds, Line and Spread  

Money Line: Chicago Bears +147 vs New York Giants -175 with Bovada

Spread: Chicago Bears +3.5 (110) vs New York Giants -3.5 (-110) with Bovada

We have a pair of surprise 2-1 teams when the Bears meet the Giants Sunday afternoon for a NFC Conference clash.

The Giants suffered a huge blow Monday night when leading wideout Sterling Shepherd was carted off the field with an apparent knee injury, and the Giants offense will suffer without Shepherd.

We have two below average scoring sides with seemingly above average defenses, and 3.5 is too many points for New York to spot the Bears.

Important trends for this matchup

Road team is 8-3 ATS in their last 11 meetingsUnderdog is 5-1 ATS in their last 6 meetings

You might also consider the Bears winning this game straight up. The Giants offense isn’t that good, and maybe the Bears defense is better than the New York offense. Especially without Shepherd in the lineup. 

Back Chicago +3.5 @ -110 With Bovada

Arizona Cardinals vs Carolina Panthers Odds, Line and Spread 

Money Line: Arizona Cardinals +112  vs Carolina Panthers -130 with Bovada

Spread: Arizona Cardinals +2.0 (-107) vs Carolina Panthers  -2.0 (-107) with Bovada

We have an interesting NFC Conference matchup between two 1-2 sides, but I’m not that sure the Panthers should be favored in this tilt.

All one has to do is look at the schedule to see why Arizona allows 29 points per game. The Rams, Chiefs and Raiders all have pretty good offenses, while Carolina has played mediocre sides in Cleveland, New York Giants and New Orleans.

The Cardinals offense has a solid roster, and they desperately need a win. The only thing stopping Arizona Sunday against the Carolina defense is the Cardinals offense.

Important trends for this matchup;

Cardinals are 23-8 ATS in their last 31 road games vs. a team with a losing home recordCardinals are 19-7-2 ATS in their last 28 road gamesPanthers are 7-19-1 ATS in their last 27 home gamesPanthers are 0-7 ATS in their last 7 home games vs. a team with a losing road record.

Back Arizona +2.0 points @ -107 With Bovada

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